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Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example
Desorption/ionization mass spectrometry (DI-MS) approaches allow for the rapid quantification of drugs in biological matrices using assays that can be validated according to regulatory guidelines. However, specific adaptations must be applied to create reliable quantification methods, depending on t...
Autores principales: | Fresnais, Margaux, Karabulut, Seda, Abou Zeed, Yasmin, Ungermann, Johannes, Benzel, Julia, Pajtler, Kristian W., Pfister, Stefan M., Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838468/ https://www.ncbi.nlm.nih.gov/pubmed/35163955 http://dx.doi.org/10.3390/molecules27030690 |
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