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Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1

Epigenetic readout of the combinatorial posttranslational modification comprised of trimethyllysine and asymmetric dimethylarginine (H3K4me3R8me2a) takes place via biomolecular recognition of tandem Tudor-domain-containing protein Spindlin1. Through comparative thermodynamic data and molecular dynam...

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Detalles Bibliográficos
Autores principales: Porzberg, Miriam R. B., Moesgaard, Laust, Johansson, Catrine, Oppermann, Udo, Kongsted, Jacob, Mecinović, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838590/
https://www.ncbi.nlm.nih.gov/pubmed/35164245
http://dx.doi.org/10.3390/molecules27030983