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Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1
Epigenetic readout of the combinatorial posttranslational modification comprised of trimethyllysine and asymmetric dimethylarginine (H3K4me3R8me2a) takes place via biomolecular recognition of tandem Tudor-domain-containing protein Spindlin1. Through comparative thermodynamic data and molecular dynam...
Autores principales: | Porzberg, Miriam R. B., Moesgaard, Laust, Johansson, Catrine, Oppermann, Udo, Kongsted, Jacob, Mecinović, Jasmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838590/ https://www.ncbi.nlm.nih.gov/pubmed/35164245 http://dx.doi.org/10.3390/molecules27030983 |
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