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Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease

A diet-induced non-alcoholic fatty liver disease (NAFLD) model causing obesity in rodents was used to examine whether sitagliptin and gliclazide therapies have similar protective effects on pathological liver change. Methods: Male mice were fed a high-fat diet (HFD) or standard chow (Chow) ad libitu...

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Detalles Bibliográficos
Autores principales: Ren, Jing, Wang, Xiaoyu, Yee, Christine, Gorrell, Mark D., McLennan, Susan V., Twigg, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838637/
https://www.ncbi.nlm.nih.gov/pubmed/35163991
http://dx.doi.org/10.3390/molecules27030727