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A Multiwell-Based Assay for Screening Thyroid Hormone Signaling Disruptors Using thibz Expression as a Sensitive Endpoint in Xenopus laevis

There is a need for rapidly screening thyroid hormone (TH) signaling disruptors in vivo considering the essential role of TH signaling in vertebrates. We aimed to establish a rapid in vivo screening assay using Xenopus laevis based on the T3-induced Xenopus metamorphosis assay we established previou...

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Detalles Bibliográficos
Autores principales: Li, Jinbo, Li, Yuanyuan, Zhu, Min, Song, Shilin, Qin, Zhanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838645/
https://www.ncbi.nlm.nih.gov/pubmed/35164063
http://dx.doi.org/10.3390/molecules27030798