New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation

Aseries of novel 1,4-disubstituted 1,2,3-triazoles were synthesized from an (R)-carvone terminal alkyne derivative via a Cu (I)-catalyzed azide–alkyne cycloaddition reaction using CuSO(4),5H(2)O as the copper (II) source and sodium ascorbate as a reducing agent which reduces Cu (II) into Cu (I). All...

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Detalles Bibliográficos
Autores principales: Oubella, Ali, Bimoussa, Abdoullah, N’ait Oussidi, Abdellah, Fawzi, Mourad, Auhmani, Aziz, Morjani, Hamid, Riahi, Abdelkhalek, Esseffar, M’hamed, Parish, Carol, Ait Itto, Moulay Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839216/
https://www.ncbi.nlm.nih.gov/pubmed/35164037
http://dx.doi.org/10.3390/molecules27030769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839216/
https://www.ncbi.nlm.nih.gov/pubmed/35164037
http://dx.doi.org/10.3390/molecules27030769

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