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Investigation of the Anticancer Effect of α-Aminophosphonates and Arylidine Derivatives of 3-Acetyl-1-aminoquinolin-2(1H)-one on the DMBA Model of Breast Cancer in Albino Rats with In Silico Prediction of Their Thymidylate Synthase Inhibitory Effect

Breast cancer is a major cause of death in women worldwide. In this study, 60 female rats were classified into 6 groups; negative control, α-aminophosphonates, arylidine derivatives of 3-acetyl-1-aminoquinolin-2(1H)-one, DMBA, DMBA & α-aminophosphonates, and DMBA & arylidine derivatives of 3...

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Detalles Bibliográficos
Autores principales: Nassan, Mohamed A., Aldhahrani, Adil, Amer, Hamada H., Elhenawy, Ahmed, Swelum, Ayman A., Ali, Omar M., Zaki, Yasser H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839308/
https://www.ncbi.nlm.nih.gov/pubmed/35164019
http://dx.doi.org/10.3390/molecules27030756