Synthesis, Nanoformulations, and In Vitro Anticancer Activity of N-Substituted Side Chain Neocryptolepine Scaffolds

The naturally occurring neocryptolepine (5-Methylindolo [2,3-b]quinoline) and its analogs exhibited prominent anticancer and antimalarial activity. However, the main problem of this class of compounds is their poor aqueous solubility, hampering their bioavailability and preventing their clinical dev...

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Detalles Bibliográficos
Autores principales: El Sayed, Ibrahim El-Tantawy, Ullah, Sami, Al-Hartomy, Omar A., Hasanein, Asmaa Mohammed, Ahmed, Abdullah A. S., Kahilo, Khaled A., El-Naggar, Mehrez E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839462/
https://www.ncbi.nlm.nih.gov/pubmed/35164289
http://dx.doi.org/10.3390/molecules27031024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839462/
https://www.ncbi.nlm.nih.gov/pubmed/35164289
http://dx.doi.org/10.3390/molecules27031024

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