Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction

Diet-related obesity is associated with increased intestinal hyperpermeability. High dietary fat intake causes an increase in colonic bile acids (BAs), particularly deoxycholic acid (DCA). We hypothesize that DCA modulates the gene expression of multiple cell junction pathways and increases intestin...

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Detalles Bibliográficos
Autores principales: Zeng, Huawei, Safratowich, Bryan D., Cheng, Wen-Hsing, Larson, Kate J., Briske-Anderson, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839472/
https://www.ncbi.nlm.nih.gov/pubmed/35163990
http://dx.doi.org/10.3390/molecules27030723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839472/
https://www.ncbi.nlm.nih.gov/pubmed/35163990
http://dx.doi.org/10.3390/molecules27030723

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