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Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein

The multidomain BAG3 protein is a member of the BAG (Bcl-2-associated athanogene) family of co-chaperones, involved in a wide range of protein–protein interactions crucial for many key cellular pathways, including autophagy, cytoskeletal dynamics, and apoptosis. Basal expression of BAG3 is elevated...

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Detalles Bibliográficos
Autores principales: Ruggiero, Dafne, Terracciano, Stefania, Lauro, Gianluigi, Pecoraro, Michela, Franceschelli, Silvia, Bifulco, Giuseppe, Bruno, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839660/
https://www.ncbi.nlm.nih.gov/pubmed/35163936
http://dx.doi.org/10.3390/molecules27030665