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Application of HPLC-QQQ-MS/MS and New RP-HPLC-DAD System Utilizing the Chaotropic Effect for Determination of Nicotine and Its Major Metabolites Cotinine, and trans-3′-Hydroxycotinine in Human Plasma Samples

The routine techniques currently applied for the determination of nicotine and its major metabolites, cotinine, and trans-3′-hydroxycotinine, in biological fluids, include spectrophotometric, immunoassays, and chromatographic techniques. The aim of this study was to develop, and compare two new chro...

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Detalles Bibliográficos
Autores principales: Baj, Jacek, Flieger, Wojciech, Przygodzka, Dominika, Buszewicz, Grzegorz, Teresiński, Grzegorz, Pizoń, Magdalena, Maciejewski, Ryszard, Flieger, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839739/
https://www.ncbi.nlm.nih.gov/pubmed/35163947
http://dx.doi.org/10.3390/molecules27030682