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Phosphate Starvation by Energy Metabolism Disturbance in Candida albicans vip1Δ/Δ Induces Lipid Droplet Accumulation and Cell Membrane Damage

Phosphorus in the form of phosphate (Pi) is an essential element for metabolic processes, including lipid metabolism. In yeast, the inositol polyphosphate kinase vip1 mediated synthesis of inositol heptakisphosphate (IP(7)) regulates the phosphate-responsive (PHO) signaling pathway, which plays an i...

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Detalles Bibliográficos
Autores principales: Peng, Xueling, Ma, Congcong, Feng, Yuxin, Zhang, Biao, Zhu, Mengsen, Ma, Tianyu, Yu, Qilin, Li, Mingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839741/
https://www.ncbi.nlm.nih.gov/pubmed/35163951
http://dx.doi.org/10.3390/molecules27030686