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An Improved Approach for Practical Synthesis of 5-Hydroxymethyl-2′-deoxycytidine (5hmdC) Phosphoramidite and Triphosphate

5-Hydroxymethyl-2′-deoxycytidine (5hmdC) phosphoramidite and triphosphate are important building blocks in 5hmdC-containing DNA synthesis for epigenetic studies. However, efficient and practical methods for the synthesis of these compounds are still limited. The current research provides an intensiv...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Zhao, Chen, Zhen-Zhen, Chi, Mei, Dong, Ying-Ying, Pu, Shou-Zhi, Sun, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839764/
https://www.ncbi.nlm.nih.gov/pubmed/35164012
http://dx.doi.org/10.3390/molecules27030749