The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding

Tuberculosis (TB), caused by the Mycobacterium tuberculosis infection, continues to be a leading cause of morbidity and mortality in developing countries. Resistance to the first-line anti-TB drugs, isoniazid (INH) and rifampicin (RIF), is a major drawback to effective TB treatment. Genetic mutation...

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Detalles Bibliográficos
Autores principales: Amusengeri, Arnold, Khan, Asifullah, Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839920/
https://www.ncbi.nlm.nih.gov/pubmed/35164151
http://dx.doi.org/10.3390/molecules27030885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839920/
https://www.ncbi.nlm.nih.gov/pubmed/35164151
http://dx.doi.org/10.3390/molecules27030885

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