Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach

In this study, a first attempt has been made to deliver levosulpiride transdermally through a thiolated chitosan microneedle patch (TC-MNP). Levosulpiride is slowly and weakly absorbed from the gastrointestinal tract with an oral bioavailability of less than 25% and short half-life of about 6 h. In...

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Detalles Bibliográficos
Autores principales: Habib, Rukhshanda, Azad, Abul Kalam, Akhlaq, Muhammad, Al-Joufi, Fakhria A., Shahnaz, Gul, Mohamed, Hanan R. H., Naeem, Muhammad, Almalki, Abdulraheem S. A., Asghar, Junaid, Jalil, Aamir, Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839939/
https://www.ncbi.nlm.nih.gov/pubmed/35160403
http://dx.doi.org/10.3390/polym14030415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839939/
https://www.ncbi.nlm.nih.gov/pubmed/35160403
http://dx.doi.org/10.3390/polym14030415

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