Disruption of Crystal Packing in Thieno[2,3-b]pyridines Improves Anti-Proliferative Activity

3-Amino-2-arylcarboxamido-thieno[2,3-b]pyridines have been shown to have anti-proliferative activity, but are also known to have poor solubility. This has been previously proposed to be due to their extensive planarity, which allows for intermolecular stacking and crystal packing. We herein report t...

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Detalles Bibliográficos
Autores principales: Haverkate, Natalie A., Leung, Euphemia, Pilkington, Lisa I., Barker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840025/
https://www.ncbi.nlm.nih.gov/pubmed/35164101
http://dx.doi.org/10.3390/molecules27030836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840025/
https://www.ncbi.nlm.nih.gov/pubmed/35164101
http://dx.doi.org/10.3390/molecules27030836

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