Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies

Trying to meet the multitarget-directed ligands strategy, a series of previously described aryl-substituted phenylalanine derivatives, reported as competitive antagonists of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, were screened in vitro for their free-radical scavengin...

Descripción completa

Detalles Bibliográficos
Autores principales: Latacz, Gniewomir, Sałat, Kinga, Furgała-Wojas, Anna, Martyniak, Adrian, Olejarz-Maciej, Agnieszka, Honkisz-Orzechowska, Ewelina, Szymańska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840081/
https://www.ncbi.nlm.nih.gov/pubmed/35164136
http://dx.doi.org/10.3390/molecules27030875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840081/
https://www.ncbi.nlm.nih.gov/pubmed/35164136
http://dx.doi.org/10.3390/molecules27030875

Ejemplares similares