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Colorectal cancer development is affected by the ECM molecule EMILIN-2 hinging on macrophage polarization via the TLR-4/MyD88 pathway

BACKGROUND: Colorectal cancer is one of the most frequent and deadly tumors. Among the key regulators of CRC growth and progression, the microenvironment has emerged as a crucial player and as a possible route for the development of new therapeutic opportunities. More specifically, the extracellular...

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Detalles Bibliográficos
Autores principales: Andreuzzi, Eva, Fejza, Albina, Polano, Maurizio, Poletto, Evelina, Camicia, Lucrezia, Carobolante, Greta, Tarticchio, Giulia, Todaro, Federico, Di Carlo, Emma, Scarpa, Melania, Scarpa, Marco, Paulitti, Alice, Capuano, Alessandra, Canzonieri, Vincenzo, Maiero, Stefania, Fornasarig, Mara, Cannizzaro, Renato, Doliana, Roberto, Colombatti, Alfonso, Spessotto, Paola, Mongiat, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840294/
https://www.ncbi.nlm.nih.gov/pubmed/35148799
http://dx.doi.org/10.1186/s13046-022-02271-y