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The Acid-Base/Deprotonation Equilibrium Can Be Studied with a MicroScale Thermophoresis (MST)

MicroScale thermophoresis (MST) is a rapidly developing bioanalytical technique used routinely for the examination of ligand-target affinity. It has never been used so far for the analysis of acid-base dissociation and the determination of pK(a) constant. This work is the-proof-of-concept of this ne...

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Detalles Bibliográficos
Autores principales: Nowak, Paweł Mateusz, Woźniakiewicz, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840468/
https://www.ncbi.nlm.nih.gov/pubmed/35163949
http://dx.doi.org/10.3390/molecules27030685