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Directed Evolution of a Nonheme Diiron N-oxygenase AzoC for Improving Its Catalytic Efficiency toward Nitrogen Heterocycle Substrates

The azoxy compounds with an intriguing chemical bond [-N=N(+)(-O(−))-] are known to have broad applications in many industries. Our previous work revealed that a nonheme diiron N-oxygenase AzoC catalyzed the oxidization of amino-group to its nitroso analogue in the formation of azoxy bond in azoxymy...

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Detalles Bibliográficos
Autores principales: Xu, Ye, Liu, Xiao-Fang, Chen, Xin-Ai, Li, Yong-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840469/
https://www.ncbi.nlm.nih.gov/pubmed/35164125
http://dx.doi.org/10.3390/molecules27030868