Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice

A family of novel efficient non-oxime compounds exhibited promising reactivation efficacy for VX and sarin inhibited human acetylcholinesterase was discovered. It was found that aromatic groups coupled to Mannich phenols and the introduction of imidazole to the ortho position of phenols would dramat...

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Detalles Bibliográficos
Autores principales: Wei, Zhao, Zhang, Xinlei, Nie, Huifang, Yao, Lin, Liu, Yanqin, Zheng, Zhibing, Ouyang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840479/
https://www.ncbi.nlm.nih.gov/pubmed/35164361
http://dx.doi.org/10.3390/molecules27031096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840479/
https://www.ncbi.nlm.nih.gov/pubmed/35164361
http://dx.doi.org/10.3390/molecules27031096

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