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Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice
A family of novel efficient non-oxime compounds exhibited promising reactivation efficacy for VX and sarin inhibited human acetylcholinesterase was discovered. It was found that aromatic groups coupled to Mannich phenols and the introduction of imidazole to the ortho position of phenols would dramat...
Autores principales: | Wei, Zhao, Zhang, Xinlei, Nie, Huifang, Yao, Lin, Liu, Yanqin, Zheng, Zhibing, Ouyang, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840479/ https://www.ncbi.nlm.nih.gov/pubmed/35164361 http://dx.doi.org/10.3390/molecules27031096 |
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