Preparation of Azithromycin Amorphous Solid Dispersion by Hot-Melt Extrusion: An Advantageous Technology with Taste Masking and Solubilization Effects

Azithromycin (AZI) is one of the most commonly used macrolide antibiotics in children, but has the disadvantages of a heavy bitter taste and poor solubility. In order to solve these problems, hot-melt extrusion (HME) was used to prepare azithromycin amorphous solid dispersion. Preliminary selection...

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Detalles Bibliográficos
Autores principales: Li, Jiale, Li, Conghui, Zhang, Hui, Gao, Xiang, Wang, Ting, Wang, Zengming, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840525/
https://www.ncbi.nlm.nih.gov/pubmed/35160485
http://dx.doi.org/10.3390/polym14030495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840525/
https://www.ncbi.nlm.nih.gov/pubmed/35160485
http://dx.doi.org/10.3390/polym14030495

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