Design, Synthesis, Spectroscopic Characterisation and In Vitro Cytostatic Evaluation of Novel Bis(coumarin-1,2,3-triazolyl)benzenes and Hybrid Coumarin-1,2,3-triazolyl-aryl Derivatives

In this work, a series of novel 1,2,3-triazolyl-coumarin hybrid systems were designed as potential antitumour agents. The structural modification of the coumarin ring was carried out by Cu(I)-catalysed Huisgen 1,3-dipolar cycloaddition of 7-azido-4-methylcoumarin and terminal aromatic alkynes to obt...

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Detalles Bibliográficos
Autores principales: Pršir, Kristina, Horak, Ema, Kralj, Marijeta, Uzelac, Lidija, Liekens, Sandra, Steinberg, Ivana Murković, Krištafor, Svjetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840664/
https://www.ncbi.nlm.nih.gov/pubmed/35163905
http://dx.doi.org/10.3390/molecules27030637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840664/
https://www.ncbi.nlm.nih.gov/pubmed/35163905
http://dx.doi.org/10.3390/molecules27030637

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