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Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer

BACKGROUND: Preclinical and epidemiological studies indicate a potential chemopreventive role of low-density lipoprotein cholesterol (LDL-C) -lowering drugs in the risks of breast cancer and prostate cancer, but the causality remains unclear. We aimed to evaluate the association of genetically proxi...

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Detalles Bibliográficos
Autores principales: Sun, Lulu, Ding, Huan, Jia, Yiming, Shi, Mengyao, Guo, Daoxia, Yang, Pinni, Wang, Yu, Liu, Fanghua, Zhang, Yonghong, Zhu, Zhengbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840684/
https://www.ncbi.nlm.nih.gov/pubmed/35151363
http://dx.doi.org/10.1186/s13058-022-01508-0