Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations

Since the efficiency in the transcription of the HIV genome contributes to the success of viral replication and infectivity, we investigated the downregulating effects of the spirobisindole alkaloids globospiramine (1), deoxyvobtusine (2), and vobtusine lactone (3) from the endemic Philippine medici...

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Detalles Bibliográficos
Autores principales: de Jesus, Ma. Sheila M., Macabeo, Allan Patrick G., Ramos, John Donnie A., de Leon, Von Novi O., Asamitsu, Kaori, Okamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840767/
https://www.ncbi.nlm.nih.gov/pubmed/35164343
http://dx.doi.org/10.3390/molecules27031078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840767/
https://www.ncbi.nlm.nih.gov/pubmed/35164343
http://dx.doi.org/10.3390/molecules27031078

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