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Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-kB Cascade: In Vitro and In Silico Investigations
Since the efficiency in the transcription of the HIV genome contributes to the success of viral replication and infectivity, we investigated the downregulating effects of the spirobisindole alkaloids globospiramine (1), deoxyvobtusine (2), and vobtusine lactone (3) from the endemic Philippine medici...
Autores principales: | de Jesus, Ma. Sheila M., Macabeo, Allan Patrick G., Ramos, John Donnie A., de Leon, Von Novi O., Asamitsu, Kaori, Okamoto, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840767/ https://www.ncbi.nlm.nih.gov/pubmed/35164343 http://dx.doi.org/10.3390/molecules27031078 |
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