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RIG-I-induced innate antiviral immunity protects mice from lethal SARS-CoV-2 infection

The SARS-CoV-2 pandemic has underscored the need for rapidly usable prophylactic and antiviral treatments against emerging viruses. The targeted stimulation of antiviral innate immune receptors can trigger a broad antiviral response that also acts against new, unknown viruses. Here, we used the K18-...

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Detalles Bibliográficos
Autores principales: Marx, Samira, Kümmerer, Beate M., Grützner, Christian, Kato, Hiroki, Schlee, Martin, Renn, Marcel, Bartok, Eva, Hartmann, Gunther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841011/
https://www.ncbi.nlm.nih.gov/pubmed/35186439
http://dx.doi.org/10.1016/j.omtn.2022.02.008