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SYT-SSX1 enhances the invasiveness and maintains stem-like cell properties in synovial sarcoma via induction of TGF-β1/Smad signaling

BACKGROUND: Synovial sarcoma (SS) is a type of soft tissue sarcoma (STS) of undetermined tissue origin, which is characterized by the recurrent pathognomonic chromosomal translocation t (X;18)(p11.2; q11.2). Studies have shown that SS is a malignant tumor originating from cancer stem cells or plurip...

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Detalles Bibliográficos
Autores principales: Qi, Yan, Dong, Shuang-Shuang, He, Yong-Lai, Liu, Zi-Han, Huang, Ya-Lan, Wang, Ning, Zhang, Zhen, Li, Zhong, Shi, Mei Er Tu He Ta Mi, Feng, Xiao, Yao, Qing, Zou, Hong, Hu, Jian-Ming, Pang, Li-Juan, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841078/
https://www.ncbi.nlm.nih.gov/pubmed/35151264
http://dx.doi.org/10.1186/s12885-022-09229-5