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SYT-SSX1 enhances the invasiveness and maintains stem-like cell properties in synovial sarcoma via induction of TGF-β1/Smad signaling
BACKGROUND: Synovial sarcoma (SS) is a type of soft tissue sarcoma (STS) of undetermined tissue origin, which is characterized by the recurrent pathognomonic chromosomal translocation t (X;18)(p11.2; q11.2). Studies have shown that SS is a malignant tumor originating from cancer stem cells or plurip...
Autores principales: | Qi, Yan, Dong, Shuang-Shuang, He, Yong-Lai, Liu, Zi-Han, Huang, Ya-Lan, Wang, Ning, Zhang, Zhen, Li, Zhong, Shi, Mei Er Tu He Ta Mi, Feng, Xiao, Yao, Qing, Zou, Hong, Hu, Jian-Ming, Pang, Li-Juan, Li, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841078/ https://www.ncbi.nlm.nih.gov/pubmed/35151264 http://dx.doi.org/10.1186/s12885-022-09229-5 |
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