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Immunohistochemistry study of tumor vascular normalization and anti-angiogenic effects of sunitinib versus bevacizumab prior to dose-dense doxorubicin/cyclophosphamide chemotherapy in HER2-negative breast cancer

PURPOSE: Tumor angiogenesis controlled predominantly by vascular endothelial growth factor and its receptor (VEGF-VEGFR) interaction plays a key role in the growth and propagation of cancer cells. However, the newly formed network of blood vessels is disorganized and leaky. Pre-treatment with anti-a...

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Detalles Bibliográficos
Autores principales: Yadav, Kritika, Lim, Joline, Choo, Joan, Ow, Samuel Guan Wei, Wong, Andrea, Lee, Matilda, Chan, Ching Wan, Hartman, Mikael, Lim, Siew Eng, Ngoi, Natalie, Tang, Siau Wei, Ang, Yvonne, Chan, Gloria, Chong, Wan Qin, Tan, Hon Lyn, Tan, Sing Huang, Goh, Boon Cher, Lee, Soo Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841320/
https://www.ncbi.nlm.nih.gov/pubmed/34928481
http://dx.doi.org/10.1007/s10549-021-06470-7