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Immunohistochemistry study of tumor vascular normalization and anti-angiogenic effects of sunitinib versus bevacizumab prior to dose-dense doxorubicin/cyclophosphamide chemotherapy in HER2-negative breast cancer
PURPOSE: Tumor angiogenesis controlled predominantly by vascular endothelial growth factor and its receptor (VEGF-VEGFR) interaction plays a key role in the growth and propagation of cancer cells. However, the newly formed network of blood vessels is disorganized and leaky. Pre-treatment with anti-a...
Autores principales: | Yadav, Kritika, Lim, Joline, Choo, Joan, Ow, Samuel Guan Wei, Wong, Andrea, Lee, Matilda, Chan, Ching Wan, Hartman, Mikael, Lim, Siew Eng, Ngoi, Natalie, Tang, Siau Wei, Ang, Yvonne, Chan, Gloria, Chong, Wan Qin, Tan, Hon Lyn, Tan, Sing Huang, Goh, Boon Cher, Lee, Soo Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841320/ https://www.ncbi.nlm.nih.gov/pubmed/34928481 http://dx.doi.org/10.1007/s10549-021-06470-7 |
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