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Role of ARHGEF3 as a GEF and mTORC2 Regulator

Guanine nucleotide exchange factors (GEFs) activate GTPases by stimulating the release of guanosine diphosphate to permit the binding of guanosine triphosphate. ARHGEF3 or XPLN (exchange factor found in platelets, leukemic, and neuronal tissues) is a selective guanine nucleotide exchange factor for...

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Detalles Bibliográficos
Autores principales: Khaliq, Sana Abdul, Umair, Zobia, Yoon, Mee-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841341/
https://www.ncbi.nlm.nih.gov/pubmed/35174167
http://dx.doi.org/10.3389/fcell.2021.806258