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Evaluation of protein descriptors in computer-aided rational protein engineering tasks and its application in property prediction in SARS-CoV-2 spike glycoprotein

The importance of protein engineering in the research and development of biopharmaceuticals and biomaterials has increased. Machine learning in computer-aided protein engineering can markedly reduce the experimental effort in identifying optimal sequences that satisfy the desired properties from a l...

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Detalles Bibliográficos
Autores principales: Lim, Hocheol, Jeon, Hyeon-Nae, Lim, Seungcheol, Jang, Yuil, Kim, Taehee, Cho, Hyein, Pan, Jae-Gu, No, Kyoung Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841378/
https://www.ncbi.nlm.nih.gov/pubmed/35222841
http://dx.doi.org/10.1016/j.csbj.2022.01.027