Biotin attenuates heat shock factor 4b transcriptional activity by lysine 444 biotinylation

Genetic mutations in HSF4 cause congenital cataracts. HSF4 exhibits both positive and negative regulation on the transcription of heat shock and non-heat shock proteins during lens development, and its activity is regulated by posttranslational modifications. Biotin is an essential vitamin that regu...

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Detalles Bibliográficos
Autores principales: Yan, Longjun, Li, Jing, Hu, Jialin, Qu, Junwei, Li, Kejia, Wang, Mingli, An, Shuang-Shuang, Ke, Cun-cun, Li, Hui, Yuan, Fengling, Guo, Weikai, Hu, Mengyue, Zhang, Jing, Yang, Zhengyan, Mu, Hongmei, zhang, Fengyan, Zhang, Jun, Cui, Xiukun, Hu, Yanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841385/
https://www.ncbi.nlm.nih.gov/pubmed/35198740
http://dx.doi.org/10.1016/j.bbrep.2022.101227

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