Model‐informed assessment of ethnic sensitivity and dosage justification for Asian populations in the global clinical development and use of cladribine tablets

Cladribine tablets have been approved in many countries for the treatment of patients with various forms of relapsing multiple sclerosis (MS). Cladribine has a unique pharmacokinetic/pharmacodynamic (PK/PD) profile with a short elimination half‐life (~ 1 day) relative to a prolonged PD effect on spe...

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Detalles Bibliográficos
Autores principales: Munafo, Alain, Terranova, Nadia, Li, Dandan, Liu, Ping, Venkatakrishnan, Karthik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841458/
https://www.ncbi.nlm.nih.gov/pubmed/34704362
http://dx.doi.org/10.1111/cts.13166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841458/
https://www.ncbi.nlm.nih.gov/pubmed/34704362
http://dx.doi.org/10.1111/cts.13166

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