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Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects

Baloxavir marboxil, a novel influenza therapeutic agent, is a prodrug rapidly metabolized into its active form, baloxavir acid, which inhibits cap‐dependent endonuclease. This study evaluated the pharmacokinetics (PKs) and safety of baloxavir acid in healthy Korean subjects and compared them with pu...

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Detalles Bibliográficos
Autores principales: Kim, Yun, Lee, Sangwon, Kim, Yohan, Jang, In‐Jin, Lee, SeungHwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841484/
https://www.ncbi.nlm.nih.gov/pubmed/34664769
http://dx.doi.org/10.1111/cts.13160