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Structural Basis for Unusual TCR CDR3β Usage Against an Immunodominant HIV-1 Gag Protein Peptide Restricted to an HLA-B*81:01 Molecule

In HIV infection, some closely associated human leukocyte antigen (HLA) alleles are correlated with distinct clinical outcomes although presenting the same HIV epitopes. The mechanism that underpins this observation is still unknown, but may be due to the essential features of HLA alleles or T cell...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Lei, Jun, San, Dan, Yang, Yi, Paek, Chonil, Xia, Zixiong, Chen, Yongshun, Yin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841528/
https://www.ncbi.nlm.nih.gov/pubmed/35173732
http://dx.doi.org/10.3389/fimmu.2022.822210