Carfilzomib inhibits the proliferation and apoptosis of multiple myeloma cells by inhibiting STAT1/COX-2/iNOS signaling pathway

BACKGROUND: The ubiquitin-proteasome pathway (UPP) plays a key role in the intracellular degradation of abnormal and misfolded proteins in eukaryotic cells. Multiple myeloma (MM) is a common hematologic malignancy caused by clonal expansion of malignant plasma cells. Proteasome-targeted drugs such a...

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Detalles Bibliográficos
Autores principales: He, Shaolong, Tian, Weiwei, Zhao, Jie, Gong, Rong, Wang, Tao, Ma, Liangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841661/
https://www.ncbi.nlm.nih.gov/pubmed/35261897
http://dx.doi.org/10.21037/tcr-21-2534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841661/
https://www.ncbi.nlm.nih.gov/pubmed/35261897
http://dx.doi.org/10.21037/tcr-21-2534

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