Fluorescent Ligand-Based Discovery of Small-Molecule Sulfonamide Agonists for GPR120

As a critical member of G protein-coupled receptors (GPCRs), G protein-coupled receptor 120 (GPR120) is a potential target for many physiological diseases, such as type 2 diabetes mellitus, inflammation, and obesity. Considering that small-molecule fluorescent ligands can combine the advantages of v...

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Detalles Bibliográficos
Autores principales: Ma, Siyue, Li, Zhenzhen, Yang, Yueli, Zhang, Ling, Li, Minyong, Du, Lupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841740/
https://www.ncbi.nlm.nih.gov/pubmed/35174139
http://dx.doi.org/10.3389/fchem.2022.816014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841740/
https://www.ncbi.nlm.nih.gov/pubmed/35174139
http://dx.doi.org/10.3389/fchem.2022.816014

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