Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice

Acute liver injury (ALI), often caused by viruses, alcohol, drugs, etc., is one of the most common clinical liver diseases. Although pyroptosis plays an important role in ALI, there is still a lack of effective clinical drugs related to this mechanism. Here, we show that phenethyl isothiocyanate (PE...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Shi, Ke, An, Ning, Li, Shuaifei, Bai, Mei, Wu, Xudong, Shen, Yan, Du, Ronghui, Cheng, Jingcai, Wu, Xuefeng, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841757/
https://www.ncbi.nlm.nih.gov/pubmed/35173734
http://dx.doi.org/10.3389/fimmu.2022.825428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841757/
https://www.ncbi.nlm.nih.gov/pubmed/35173734
http://dx.doi.org/10.3389/fimmu.2022.825428

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