Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report

Docetaxel therapy occasionally causes severe and life-threatening toxicities. Some docetaxel toxicities are related to exposure, and inter-individual variability in exposure has been described based on genetic variation and drug-drug interactions that impact docetaxel clearance. Cytochrome P450 3A4...

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Detalles Bibliográficos
Autores principales: Powell, Nicholas R., Shugg, Tyler, Ly, Reynold C., Albany, Costantine, Radovich, Milan, Schneider, Bryan P., Skaar, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841796/
https://www.ncbi.nlm.nih.gov/pubmed/35174070
http://dx.doi.org/10.3389/fonc.2021.809527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841796/
https://www.ncbi.nlm.nih.gov/pubmed/35174070
http://dx.doi.org/10.3389/fonc.2021.809527

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