Stability of polygenic scores across discovery genome-wide association studies

Polygenic scores (PGS) are commonly evaluated in terms of their predictive accuracy at the population level by the proportion of phenotypic variance they explain. To be useful for precision medicine applications, they also need to be evaluated at the individual level when phenotypes are not necessar...

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Detalles Bibliográficos
Autores principales: Schultz, Laura M., Merikangas, Alison K., Ruparel, Kosha, Jacquemont, Sébastien, Glahn, David C., Gur, Raquel E., Barzilay, Ran, Almasy, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841810/
https://www.ncbi.nlm.nih.gov/pubmed/35199043
http://dx.doi.org/10.1016/j.xhgg.2022.100091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841810/
https://www.ncbi.nlm.nih.gov/pubmed/35199043
http://dx.doi.org/10.1016/j.xhgg.2022.100091

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