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Compounds targeting GPI biosynthesis or N-glycosylation are active against Plasmodium falciparum

The emergence of resistance to first-line antimalarials, including artemisinin, the last effective malaria therapy in some regions, stresses the urgent need to develop new effective treatments against this disease. The identification and validation of metabolic pathways that could be targeted for dr...

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Detalles Bibliográficos
Autores principales: Fenollar, Àngel, Ros-Lucas, Albert, Pía Alberione, María, Martínez-Peinado, Nieves, Ramírez, Miriam, Ángel Rosales-Motos, Miguel, Y. Lee, Ling, Alonso-Padilla, Julio, Izquierdo, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841962/
https://www.ncbi.nlm.nih.gov/pubmed/35222844
http://dx.doi.org/10.1016/j.csbj.2022.01.029