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Compounds targeting GPI biosynthesis or N-glycosylation are active against Plasmodium falciparum
The emergence of resistance to first-line antimalarials, including artemisinin, the last effective malaria therapy in some regions, stresses the urgent need to develop new effective treatments against this disease. The identification and validation of metabolic pathways that could be targeted for dr...
Autores principales: | Fenollar, Àngel, Ros-Lucas, Albert, Pía Alberione, María, Martínez-Peinado, Nieves, Ramírez, Miriam, Ángel Rosales-Motos, Miguel, Y. Lee, Ling, Alonso-Padilla, Julio, Izquierdo, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841962/ https://www.ncbi.nlm.nih.gov/pubmed/35222844 http://dx.doi.org/10.1016/j.csbj.2022.01.029 |
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