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T lymphocyte-derived extracellular vesicles aggravate abdominal aortic aneurysm by promoting macrophage lipid peroxidation and migration via pyruvate kinase muscle isozyme 2

T lymphocyte and macrophage infiltration in the aortic wall is critical for abdominal aortic aneurysm (AAA). However, how T lymphocytes interact with macrophages in the pathogenesis of AAA remains largely uncharacterized. In an elastase-induced murine AAA model, we first found that the expression of...

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Detalles Bibliográficos
Autores principales: Dang, Guohui, Li, Tianrun, Yang, Dongmin, Yang, Guangxin, Du, Xing, Yang, Juan, Miao, Yutong, Han, Lulu, Ma, Xiaolong, Song, Yuwei, Liu, Bo, Li, Xuan, Wang, Xian, Feng, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842084/
https://www.ncbi.nlm.nih.gov/pubmed/35149342
http://dx.doi.org/10.1016/j.redox.2022.102257