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Large‐scale analysis of Drosophila core promoter function using synthetic promoters

The core promoter plays a central role in setting metazoan gene expression levels, but how exactly it “computes” expression remains poorly understood. To dissect its function, we carried out a comprehensive structure–function analysis in Drosophila. First, we performed a genome‐wide bioinformatic an...

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Detalles Bibliográficos
Autores principales: Qi, Zhan, Jung, Christophe, Bandilla, Peter, Ludwig, Claudia, Heron, Mark, Sophie Kiesel, Anja, Museridze, Mariam, Philippou‐Massier, Julia, Nikolov, Miroslav, Renna Max Schnepf, Alessio, Unnerstall, Ulrich, Ceolin, Stefano, Mühlig, Bettina, Gompel, Nicolas, Soeding, Johannes, Gaul, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842121/
https://www.ncbi.nlm.nih.gov/pubmed/35156763
http://dx.doi.org/10.15252/msb.20209816