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Proline‐rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor‐mediated synaptic transmission

BACKGROUND: Proline‐rich transmembrane protein 2 (PRRT2) is a neuron‐specific protein associated with seizures, dyskinesia, and intelligence deficit. Previous studies indicate that PRRT2 regulates neurotransmitter release from presynaptic membranes. However, PRRT2 can also bind AMPA‐type glutamate r...

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Detalles Bibliográficos
Autores principales: Feng, Hao‐Yang, Qiao, Fengchang, Tan, Jianxin, Zhang, Xiaozuo, Hu, Ping, Shi, Yun Stone, Xu, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842155/
https://www.ncbi.nlm.nih.gov/pubmed/34997978
http://dx.doi.org/10.1002/jcla.24196