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Proline‐rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor‐mediated synaptic transmission
BACKGROUND: Proline‐rich transmembrane protein 2 (PRRT2) is a neuron‐specific protein associated with seizures, dyskinesia, and intelligence deficit. Previous studies indicate that PRRT2 regulates neurotransmitter release from presynaptic membranes. However, PRRT2 can also bind AMPA‐type glutamate r...
Autores principales: | Feng, Hao‐Yang, Qiao, Fengchang, Tan, Jianxin, Zhang, Xiaozuo, Hu, Ping, Shi, Yun Stone, Xu, Zhengfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842155/ https://www.ncbi.nlm.nih.gov/pubmed/34997978 http://dx.doi.org/10.1002/jcla.24196 |
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