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Assessing Gq-GPCR–induced human astrocyte reactivity using bioengineered neural organoids

Astrocyte reactivity can directly modulate nervous system function and immune responses during disease and injury. However, the consequence of human astrocyte reactivity in response to specific contexts and within neural networks is obscure. Here, we devised a straightforward bioengineered neural or...

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Detalles Bibliográficos
Autores principales: Cvetkovic, Caroline, Patel, Rajan, Shetty, Arya, Hogan, Matthew K., Anderson, Morgan, Basu, Nupur, Aghlara-Fotovat, Samira, Ramesh, Srivathsan, Sardar, Debosmita, Veiseh, Omid, Ward, Michael E., Deneen, Benjamin, Horner, Philip J., Krencik, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842185/
https://www.ncbi.nlm.nih.gov/pubmed/35139144
http://dx.doi.org/10.1083/jcb.202107135